Midway via his career, Cees Dekker reinvented himself. Immediately after several years of hardcore physics, he shifted his concentrate to ‘nanobiology’ for the change of the millennium. A time period he coined himself, as being a subject of reality.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules
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Nanofabrication of electrodes with sub-five nm spacing for transport experiments on solitary molecules and metal clusters
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart style in 2005. (nl)
SMC complexes can pass physical roadblocks larger than their ring sizing, indicating a nontopological system for DNA loop extrusion
We use nanofabricated microfluidic structures to sample spatial boundaries for micro organism and biomimetic vesicles with reconstituted protein networks which assess the fundamental function of spatial confinement in the molecular and cellular level. Our jobs involve the subsequent:
Studying DNA loop extrusion by SMC proteins for chromosome architecture with solitary-molecule assays.
The rotors harness Strength from a nanoscale h2o and ion circulation that's created by a static chemical or electrochemical probable gradient inside the nanopore, which are founded by way of a salt gradient or used voltage, respectively. These synthetic nanoengines self-organize and run autonomously in physiological situations, ceesdekker suggesting ways to setting up Power-transducing motors at nanoscale interfaces.
Bulk-area coupling identifies the mechanistic relationship between Min-protein patterns in vivo and in vitro
[14] In 2005 Dekker grew to become involved in Netherlands-vast conversations about Intelligent Style and design, a movement that he has due to the fact clearly distanced himself from. Dekker advocates that science and religion are usually not in opposition but could be harmonized.
Nanoscientist Cees Dekker is really an amiable and flamboyant gentleman who appears much young in comparison to the sixty two a long time he really is – fashionable Eyeglasses, psychedelic shirt, participating smile – but not just one to waste time. He requires his time, but not more than important.
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2004, discovery of recent physics in translocation of DNA by way of nanopores; 1st experimental research of ions conduction in nanofluidic channels; to start with electrochemistry with particular person single-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; very first electrical docking of microtubules on kinesin-coated nanostructures; first biophysics characterization with the mechanical Qualities of double-stranded RNA; and to start with solitary-molecule study of DNA translocation by a restriction-modification enzyme.